RESUMO
A 66-year-old man, who was discovered to have human immunodeficiency virus (HIV) infection 22 months previously and was treated with highly active antiretroviral (HAART) therapy, developed giant cell carcinoma of the lung. In English literature, this is the first case of such cell type of lung cancer during HAART therapy. Since giant cell carcinoma of the lung occurs mainly in elderly men who smoke heavily, there may not be a possibility that the HIV or HAART was causative in our patient.
Assuntos
Síndrome da Imunodeficiência Adquirida/complicações , Carcinoma de Células Gigantes/diagnóstico , Neoplasias Pulmonares/diagnóstico , Síndrome da Imunodeficiência Adquirida/tratamento farmacológico , Idoso , Terapia Antirretroviral de Alta Atividade , Carcinoma de Células Gigantes/etiologia , Carcinoma de Células Gigantes/patologia , Evolução Fatal , Infecções por HIV/complicações , Infecções por HIV/tratamento farmacológico , Humanos , Neoplasias Pulmonares/etiologia , Neoplasias Pulmonares/patologia , MasculinoRESUMO
Pleomorphic (spindle/giant cell) carcinoma (PC) is one subset of large cell carcinoma. It is well known that PC patients have a poor survival rate. This report describes a 68-year-old man with PC. The patient's tumor had a massive pleural effusion. A left lower lobectomy and partial resection of the left diaphragm, peritoneum, and parietal pleura were performed to remove the tumor. Numerous asbestos particles were found in the left lower lobe. This is the first reported case of PC which may have been caused by asbestos particles. Further investigation is needed into whether asbestos exposure causes PC.
